Enlarge/ Members of the public queue outside a pharmacy to receive COVID-19 antigen tests in Paris on January 6, 2022. (credit: Getty | LUDOVIC MARIN)
Omicron subvariants BA.4 and BA.5 are on the rise in the European Union, spurring officials there to warn that a surge of COVID-19 cases will likely follow in the coming weeks.
In an alert Monday, the European Center for Disease Prevention and Control cautioned that various factors would influence how bad the expected BA.4/BA.5 wave will be. Those factors include the extent of vaccination and past infection in the population, as well as timing since those events because protection from both wanes over time.
BA.4 and BA.5 are clumped together because they share the same mutations in the genetic coding for their spike proteins, though they have differing mutations elsewhere in their genome. Both have a transmission advantage over the initial omicron subvariant, BA.1, as well as subvariants BA.2 and BA.2.12.1.
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